Top ePRO Companies & CTMS with ePRO Integration
Electronic patient-reported outcomes (ePRO) let trial participants report symptoms and quality-of-life data directly, improving data quality and reducing site burden. The companies below offer ePRO either as a standalone capability or integrated into a broader CTMS, based on the ePRO Integration tags in our directory.
Top ePRO Companies & Platforms
1. Ennov
Ennov integrates ePRO within its end-to-end clinical suite, alongside clinical data management, regulatory documentation, and pharmacovigilance. Sponsors get patient-reported data feeding into a single authoritative source for the whole trial.
Key Features: ePRO Integration, Clinical Trial Management Systems, EDC Data Management
2. Clinion
Clinion offers eCOA/ePRO as part of its integrated, AI-enabled platform that also includes CTMS, EDC, RTSM, and eTMF. Patient-reported outcomes connect directly to the rest of the study data for real-time visibility.
Key Features: ePRO Integration, Clinical Trial Management Systems, EDC Data Management
3. ClinicalPURSUIT
ClinicalPURSUIT builds ePRO into its intelligent EDC and CTMS platform, alongside clinical randomization (IRT) and trial supply management (RTSM). It's designed for rapid study build with accurate, patient-driven data capture.
Key Features: ePRO Integration, Electronic Data Capture, Clinical Randomization Technology
Learn more about ClinicalPURSUIT
4. Sitero
Sitero's Mentor platform pairs CTMS and EDC with ePRO integration, supported by a full clinical operations and data management services team. It suits sponsors wanting patient-reported outcomes within an end-to-end managed solution.
Key Features: ePRO Integration, Clinical Trial Management Systems, Site Management and Monitoring
5. Mosio
Mosio specializes in participant communication and ePRO data collection, with automated messaging, two-way text messaging, appointment reminders, and REDCap integration. It's a strong fit for academic, hospital, and public-health studies that engage participants by mobile.
Key Features: Clinical Trial Management, ePRO Data Collection, REDCap Integration
How to Evaluate ePRO Solutions
When choosing an ePRO company or CTMS with ePRO integration:
- Integration Depth - Does ePRO feed directly into your EDC/CTMS, or require export?
- Participant Experience - Mobile apps, SMS, and reminders that drive compliance
- Data Quality - Validation, time-stamping, and audit trails on patient entries
- Therapeutic Fit - Diary frequency and question types for your study design
- Interoperability - Integrations such as REDCap or your existing data tools
Frequently Asked Questions
What is an ePRO company?
An ePRO company provides technology for capturing electronic patient-reported outcomes, data reported directly by trial participants through apps, web portals, or text messaging. Some, like Mosio, focus on patient engagement and data collection, while others such as Ennov, Clinion, and Sitero embed ePRO inside a full CTMS.
What is the difference between ePRO and eCOA?
ePRO (electronic patient-reported outcomes) is a subset of eCOA (electronic clinical outcome assessments). eCOA also includes clinician-reported and observer-reported outcomes. Clinion, for instance, offers eCOA capabilities that encompass ePRO.
Can I get ePRO and a CTMS from one vendor?
Yes. Ennov, Clinion, ClinicalPURSUIT, and Sitero all integrate ePRO with their CTMS and EDC, so patient-reported data and operational data live in one connected system rather than separate tools.
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